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Exothera Enters Industrial Scale AAV Manufacturing Collaboration

With partners LogicBio and Polyplus, the project aims to demonstrate the scalability and reproducibility of Exothera's AAV production processes.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Exothera SA has entered a collaboration with LogicBio Therapeutics and Polyplus-transfection SA for the development of a highly scalable AAV manufacturing platform with a capacity from 200 L to 2,000 L. Adeno-associated viruses (AAV) are non-enveloped, non-pathogenic viruses largely used as drug delivery vectors for biotherapeutics, like gene therapies and vaccines. Although the application of AAV is spreading rapidly, the industry is struggling to find cost-effective manufacturing strategies...

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